The Government Office for Technology Transfer (GOTT) has published guidance to assist public sector bodies (PSBs) in commercialising Knowledge Assets (KAs) outside the public sector while complying with the Re-use of Public Sector Information Regulations 2015 (RPSIR 2015), SI 2015/1415 and Crown copyright. The Information Commissioner’s Office enforces RPSIR 2015, SI 2015/1415, which generally apply to information produced within a PSB’s public task, excluding computer programs; PSBs must meet duties of competition, cost-recovery, fairness, and transparency, with limited exceptions. Crown copyright protects works created by Crown servants and is typically licensed under the Open Government Licence (OGL), though alternative terms require a delegation of authority from the National Archives. For commercialisation, PSBs should define objectives, assess KA composition, and consider licensing routes including OGL, Delegation-based licensing, assignment (for Crown works only), and other UK Government Licensing Framework options. The guidance includes tools to support decision-making and applies to both Crown and non-Crown contexts.