This tracker tool tracks and summarises key new legislation and consultations in England and Wales linked to the regulation of chemicals and hazardous substances including the regime for the Registration, Evaluation and Authorisation of Chemicals (REACH), the regime for Classification, Labelling and Packaging of chemicals (CLP), Prior Informed Consent (PIC), pesticides, biocides, persistent organic pollutants (POPs), ozone depleting substances (ODS), and fluorinated greenhouse gases (F-gases). Following Brexit, EU regulations relating to chemicals regulation have been retained in Great Britain, with amendments. In Northern Ireland, the EU regimes continue to apply due to the application of the Northern Ireland Protocol (now known as the Windsor Framework), save in relation to the POPs regime which is UK-wide. The following regimes apply: • UK REACH, see Practice Note: UK REACH: Assimilated Regulation (EC) No 1907/2006—snapshot • GB CLP, see Practice Note: GB classification, labelling and packaging of substances and mixtures (CLP): Retained Regulation (EC) 1272/2008—snapshot • GB PIC, see Practice Note: GB Prior Informed Consent (PIC) Assimilated Regulation (EU) No 649/2012—snapshot • GB Biocides, see