This Practice Note explains the procedure involved in appealing sentences passed in health and safety cases and explores the approach to sentencing taken by the Court of Appeal (Criminal Division) in cases involving challenges to sentences imposed for health and safety breaches. It covers sentencing very large organisations for health and safety breaches, the impact of a fatality on sentence, the effect of operating profit on appeal, the reduction in sentences passed on public bodies, new evidence in appeals against sentence in the Court of Appeal as well as skeleton arguments and costs in health and safety appeals against sentence.