This Practice Note explains the use of confiscation orders to recover the proceeds of crime generated by regulatory breaches. It covers the power of regulatory bodies (in addition to the CPS) to bring confiscation proceedings following conviction for regulatory offences in England and Wales, the key provisions under the Proceeds of Crime Act 2002 (POCA 2002) relating to the calculation of benefit from general or particular criminal conduct, issues that arise in regulatory cases so far as confiscation orders are concerned (namely, ascertaining benefit, applying the assumptions, proportionality and the concept of lifting or disregarding the corporate veil) and sets out some practical considerations for those prosecuting and defending confiscation proceedings in regulatory cases.