This Practice Note is part of a suite of Practice Notes providing practical guidance on professional fitness to practice (FtP) proceedings before the healthcare regulators. This Practice Note provides a guide to General Pharmaceutical Council (GPhC) who regulate pharmacists, pharmacy technicians and pharmacies in Great Britain. It covers FtP proceedings, including the legislative framework, the FtP proceedings, investigations and applications to be restored to the Register and disqualification proceedings. It should be read in conjunction with Practice Notes on Common Principles in fitness to practice proceedings and Criminal Proceedings in healthcare regulatory proceedings.