This Practice Note explains how the UK financial sanctions regime applies to charities and highlights the significant legal and compliance risks they may face. It outlines how sanctions exposure can arise through donors, trustees, partners, subcontractors, beneficiaries and humanitarian operations, and examines the legal and regulatory consequences of non-compliance. The Practice Note also provides practical guidance on managing these risks through sanctions screening, due diligence, ongoing monitoring, the use of OFSI licences and applicable exemptions, and effective governance and trustee oversight. In addition, it considers reporting obligations and the interaction between financial sanctions, charity law, anti-money laundering requirements and counter-terrorism legislation.Financial sanctions overviewUnder the UK sanctions framework established by the Sanctions and Anti-Money Laundering Act 2018 (SAMLA 2018) financial sanctions typically prohibit making funds or economic resources available to, or for the benefit of, designated persons—individuals, entities, or groups listed by the UK government as sanctions targets. The prohibitions are broad: it is not only direct transfers that are restricted, but any dealing which makes funds or economic resources