This Practice Note explores the concept of supply chain sustainability within the broader context of sustainable procurement and environmental, social and governance (ESG) performance, with a specific focus on key themes within private sector practices in the UK and EU. It provides practical guidance on establishing a supplier code of conduct and developing a comprehensive supply chain sustainability programme that addresses key issues such as human rights, labour standards, environmental impacts, corruption, deforestation, litigation exposure, and risk management. Public procurement is excluded from the scope of this note.