The appropriate authority1 must exercise his functions under the Animals (Scientific Procedures) Act 1986 with a view to ensuring compliance with the principles of replacement, reduction and refinement2.
For the purposes of the Animals (Scientific Procedures) Act 1986:
(1) the principle of replacement is the principle that, wherever possible, a scientifically satisfactory method or testing strategy not entailing the use of protected animals3 must be used instead of a regulated procedure4;
(2) the principle of reduction is the principle that whenever a programme of work involving the use of protected animals is carried out the number of protected animals used
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